Pale yellow powder or pale yellow crystalline powder
Safety Information of 10-Hydroxycamptothecin (cas number:19685-09-7) as below:
NONH for all modes of transport
Packing & Storage:
Packing with IATA required carton with 5kg/carton, or as customer required.
Stored in a cool, dry and dark place, shelf life 24 months.
1. (S)-10-Hydroxycamptothecin is the natural starting material of Irinotecan HCl.
2. (S)-10-Hydroxycamptothecin is the natural starting ingredient of 7-Ethyl-10-Hydroxycamptothecin(SN-38).
3. (S)-10-Hydroxycamptothecin is the natural starting ingredient of Topotecan HCl
4. This compound 10-hydroxycamptothecin is a featured product for Apoptosis research. Function: 10-hydroxycamptothecin showed remarkable anticancer activity in preliminary clinical trials by inhibiting the DNA enzyme topoisomerase I (topo I). (S)-10-Hydroxycamptothecin is a clinical therapy agent against hepatoma. Natural origins of camptothecin:
1. Camptotheca acuminata (Camptotheca, Happy tree), a tree native to Hunan ,Guangxi, Sichuan province of China. Camptotheca acuminata used as a cancer treatment in Traditional Chinese Medicine.Generally, the leaves and the fruits of happy tree are applied for the extraction of camptothecin.
2. Nothapodytes pittosporoides(Mappia), a tree wild spread in Hunan ,Guangxi, Sichuan province of China. The root of the tree is applied for the extraction of campothecin, most of this origin is applied for R&D.
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